Interventions in acute ilio-femoral DVT: 5 years’ institutional experience

S. Visvesh1, Nedounsejiane Mandjiny2

1Dr NB Vascular Surgery Resident, Kauvery Hospital, Cantonment, Trichy

2Senior Consultant Vascular & Endovascular Surgeon, Kauvery Hospital, Cantonment, Trichy

Background

The Prevailing perception among medical professional, is that anticoagulation is the only treatment for DVT?

We have surgical options too,

  • CDT – Catheter Directed Thrombolysis
  • PMT – Pharmaco Mechanical Thrombectomy
  • Iliac vein angioplasty and stenting
  • IVC filter placement

Who Should Undergo Surgical Intervention and when?

  • Young to middle aged & fit patients
  • Extensive ilio femoral / caval DVT
  • Poor response to therapeutic anticoagulation
  • May Thurner Syndrome

It all should be done Less than 2 weeks.

Classical May Thurner Syndrome

M/c (Medical Cause) in young to middle aged women with acute left leg pain & swelling

Address: DVT + Narrowing

Rationale of Audit

  • Decrease clot burden
  • Relieve acute symptoms
  • Prevent PE
    • Leading preventable cause of death
    • 3 rd m/c cause of in-hospital mortality
  • Reduce the risk of PTS

Post Thrombotic Syndrome

  • Spectrum of venous disease that affects the LL.
  • Varicose veins, chronic debilitating pain, intractable edema, skin changes, venous ulcer
  • Leg cramping, pruritis, fatigue, heaviness, venous claudication, paresthesias.
  • 50% leg thrombi resolve spontaneously.
  • 20 to 50 % pts. from a few months to 2 years following a LL DVT d/t incomplete recanalisation.

Investigation

CT-Chest, Abdomen and Pelvis with Contrast

Pulmonary Embolism

Mid-thigh circumference

Our Intervention Data- Acute Ilio-femoral DVT

  • Study Period: March 2019- March 2025
  • Study Population: 48 / 310 (15%)

Results

Demographics – Gender

Males – 20 (42%)

Females – 28 (58%)

Age Group

AgeNo. of Population
20 –30years4 (8%)
30 – 40 years7 (15%)
40 - 50 years15 (31%)
50 – 60 years14 (29%)
60 – 70 years6 (13%)
70 – 80 years2 (4%)

Types

  • Provoked – 7 (15%)
  • Unprovoked – 41 (85%)
  • Pulmonary embolism – 15 (31.25%)

Procedural Details

  • IVC filter placement prior to CDT – 10 (21%)
  • CDT + Balloon venoplasty – 11 (23%)
  • CDT + Iliac vein stenting – 33 (69%)
  • Pharmaco Mechanical Thrombectomy (PMT) – 2 (4%) (Angioget-1, Penumbra-1)
  • IVC filter retrieval – 7

Procedural Details

Procedural Images

May Thurner Syndrome

Before

After

Follow Up

  • From 2 months to 5 years
  • Clinical examinations & Doppler US – stent patency
  • IVC Filter removal after 45-60 days.

Outcomes

Positive outcomes

  • Technical success – 96%
  • 95% (46 out of 48 patients) – complete recovery
    • Reduction of swelling (mid-thigh & mid leg circumference)
    • Reduction of pain (VAS Score)
  • None developed PTS in the follow up period.

Mortality

  • One Mortality – 2%
  • On table Pulmonary Embolism (2.1%)

Complications

  • No major bleeding (IC, GI bleed)
  • 4% access site hematomas (2 out of 48) – Compression dressing
  • Stent thrombosis – 3 out of 33 (9%) – default medications

Objectives of CDT in Acute proximal DVT

  • Relieve symptoms
  • Reduce the incidence of PE
  • Reduce the risk of developing PTS
  • Prevent chronic venous insufficiency
  • Plays a crucial role in minimizing both short-term and long-term complications associated with DVT.

Reference

  • Vedantham S, Goldhaber SZ, Julian JA, Kahn SR, Jaff MR, Cohen DJ, et al. Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis. N Engl J Med. 2017 Dec 7;377(23):2240-2252.
Kauvery Hospital