Liver failure is a situation where the liver has lost almost all its functionality, due to one or more reasons. This can be either acute, which develops over a period of a few weeks and shows severe symptoms, or chronic, which develops over a couple of years and shows moderate symptoms. In the last stage is called end-stage liver disease, none of the other treatments may work, and liver transplantation is the only option.
Livers can be transplanted from a healthy, living donor or a donor who has died recently (cadaver) from either a heart condition, or a brain-dead person whose heart has stopped working. A part of the liver is taken in case of living donors. This is acceptable as the incomplete liver grows to full size in a couple of months, for both donor and recipient. Living donors can be a family member, friend or an anonymous donor. Both children and adults can receive a donor’s liver and further, the same liver can be used for two people, which is done in the case of cadaver donations. The left part of the liver is used for children and the right part for adults.
Liver transplantations are fairly common. In the US alone, there were 7100 transplants done in 2015. The number should be higher for India. They are also fairly successful. Unlike the US where extensive data on liver transplants is maintained and published, such data for India is not easily available. But the American figures can be applied to India or any part of the world for that matter. Across both adult and pediatric transplantation, living and cadaver donations, the success rates are as follows.
After 1 year of the transplant surgery, 86 percent of patients were still alive. After 3 and 5 years of surgery, these figures were 78 percent and 72 percent. 53 percent of recipients were still alive 20 years after the surgery. All these explain the popularity of liver transplantation, and the long waiting lists in every country of the world. A ‘MELD’ score is used to move people up and down the waiting list depending on their present condition and some other parameters.
Screening of donor and recipient, suitability assessment of the donation, preparing for surgery, what happens during surgery – are all vast topics in themselves. For the purpose of this article, we will focus on life after transplantation.
After the surgery, the patient stays in the hospital for 7-10 days where his/her condition is constantly monitored, and then discharged. The patient’s home and immediate surroundings must be as clean as possible, since infection is one of the risks after the surgery. Infection can happen from virus, bacteria and fungi.
There are specific dos and don’ts about taking care of the surgery wound, and the doctor will tell the patient at the time of discharge. Other than that …
Since there are many health risks or side-effects after the surgery, various medicines are given to reduce the risk. The new liver can be rejected by the body; so immunosuppressant drugs are given.
The person can get back to work in 3 months’ times but all the rules about hygienic environment and personal hygiene described above will apply.
Mild and moderate exercise can be resumed 3-6 months after the surgery.
The transplanted liver is supposed to last a lifetime if one takes good care of it. This will reduce the necessity of a re-transplant. If you or any of your dear ones have received a liver transplant recently, stay in touch with a hepatologist or liver specialist at a reputed hospital. There may be many more dos and don’ts than the above, depending on your unique situation, so he/she will advise you on the same. This will go a long way in making your transplant successful and help you live a normal, healthy life.
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1. How successful are liver transplants?
Liver transplant success rates are high, with about 86% of patients still alive after one year, and 72% after five years.
2. What precautions should I take after liver transplant surgery?
Maintain a hygienic environment, adhere to personal hygiene practices, take prescribed medications regularly, and attend follow-up appointments.
3. When can I return to work after a liver transplant?
Most patients can resume work within three months after surgery, following proper hygiene and health guidelines.
4. Can I engage in physical activities after a liver transplant?
Mild to moderate exercise can be resumed after 3-6 months, avoiding contact sports and opting for low-impact activities like walking or badminton.
5. What dietary restrictions should I follow post-transplant?
Consume clean, freshly prepared foods rich in vegetables and whole grains, avoiding street food, alcohol, and high-fat or processed foods.
6. How long does a transplanted liver last?
With proper care, a transplanted liver is expected to last a lifetime, reducing the need for re-transplantation. Regular follow-ups with a hepatologist are essential for long-term success.
Reviewed by Dr Suresh S Venkita, Group Medical Director, Kauvery Hospitals
Kauvery Hospital is globally known for its multidisciplinary services at all its Centers of Excellence, and for its comprehensive, Avant-Grade technology, especially in diagnostics and remedial care in heart diseases, transplantation, vascular and neurosciences medicine. Located in the heart of Trichy (Tennur, Royal Road and Alexandria Road (Cantonment), Chennai, Hosur, Salem, Tirunelveli and Bengaluru, the hospital also renders adult and pediatric trauma care.
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